C-Type Natriuretic Peptides in Coronary Disease
نویسندگان
چکیده
منابع مشابه
Natriuretic peptides in unstable coronary artery disease.
Patients with unstable coronary artery disease (CAD), i.e., unstable angina or non-ST-elevation myocardial infarction, vary widely in clinical presentation, prognosis and response to treatment. To select appropriate therapy, early risk stratification has become increasingly important. This review focuses on the emerging role of natriuretic peptides in the early assessment of patients with unsta...
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-type natriuretic peptides (BNP and N-terminal [NT]roBNP) have been shown to be extremely helpful in the iagnosis, prognosis, and monitoring of therapy of patients ith heart failure (HF) (1). These neurohormones are preominately secreted from the left and the right cardiac ventricle n response to cardiac stress. The BNPs can be seen as uantitative markers of HF summarizing the extent of systoli...
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In mammals, natriuretic peptides (NPs) lower blood pressure, reduce blood volume and broadly inhibit cardiovascular remodeling. NPs are often referred to as cardiac hormones, though they also have integral roles in regulating vascular tone, endothelial remodeling and inhibiting vascular smooth muscle cell hypertrophy. Two NPs [atrial (ANP) and C-type (CNP)] have been identified as endogenous co...
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Cardiovascular responses were compared with equimolar infusions of B-type (BNP) and C-type (CNP) with atrial natriuretic peptide (ANP) in conscious, instrumented dogs. On separate days, each natriuretic peptide or vehicle was infused (intravenously) at step-up doses of 2, 5, 10, and 20 pmol ⋅ kg-1 ⋅ min-1(20 min each dose) to increase circulating levels of the infused peptide from ∼2- to 20-fol...
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BACKGROUND AND OBJECTIVES B-type natriuretic peptide (BNP) and amino-terminal pro-B-type natriuretic peptide (NT-proBNP) are biomarkers of cardiovascular disease that is common in patients with chronic kidney disease (CKD). Conflicting data on the influence of glomerular filtration rate (GFR) on BNP and NT-proBNP levels in CKD may stem from failure to account fully for the effects of coexistent...
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ژورنال
عنوان ژورنال: Clinical Chemistry
سال: 2017
ISSN: 0009-9147,1530-8561
DOI: 10.1373/clinchem.2016.257816